Telehealth can feel effortless, or it can feel like a series of small delays. The difference often comes down to the API layer behind scheduling, join links, security, and post-visit records.
This article compares six telehealth API tools that support real clinical workflows, from click-to-join visits and waiting rooms to captions, recordings, and analytics.
It also highlights where each product fits best, such as live consultations, asynchronous video intake, or training sessions. If you are building virtual care into an app, these details matter. They shape no-show rates, staff workload, and how reliably teams can review what happened later.
iotum
Telehealth works best when it feels simple for patients and dependable for clinicians. That is the standard these API tools are judged against. This section looks at iotum, a telehealth video and voice conferencing API built for healthcare use cases, with scheduling, remote visit workflows, and reporting built in.
It matters for providers that need virtual care to run smoothly across devices, reduce missed appointments, and keep records consistent across teams. The goal is not flashy features. It has fewer delays, clearer handoffs, and a better experience on both sides of the call.
iotum Key Features
iotum Pros
Permission and security expectations are baked into the product story. The site highlights HIPAA-aligned conferencing, data sovereignty across regions, and privacy controls like Meeting Lock, one-time access codes, and secure rooms. It is also built on WebRTC standards and hosted on AWS and DigitalOcean, with “no offshore development” stated.
Operationally, the mix of scheduling, reminders, and click-to-join can reduce join friction, while built-in recording, transcriptions, and analytics can support follow-ups and quality review without extra tooling.
iotum Best Use Case
Sendbird Video
Sendbird Video provides another option for healthcare providers who need video communication capabilities.
Sendbird Video Key Features
Sendbird's platform comes with these features for telehealth applications:
Sendbird Video Pros
We integrated messaging and calling completely to create a unified communication experience for telehealth apps.
The platform provides extensive SDKs for iOS, Android, JavaScript, React Native, and Unity that make development easier across different environments.
Their high-quality media transmission keeps latency low, which makes a vital difference during time-sensitive medical consultations.
The platform's custom metadata capabilities help healthcare providers create individual-specific experiences by attaching contextual information to each call.
Their cloud infrastructure ended up supporting millions of users globally and meets data governance and latency requirements for healthcare organizations of all sizes.
Sendbird Video Best Use Case
Healthcare organizations like United Healthcare, Grand Rounds, Accolade, and Docplanner have chosen Sendbird Video because it meets HIPAA compliance requirements.
Doctors can securely talk to patients during virtual healthcare consultations while meeting all health data regulations.
The personal, supportive nature of Sendbird's video calling works great for telemental wellness services.
Patients in underserved areas can connect with specialists without traveling, making remote healthcare delivery effective.
Ziggeo
Ziggeo earned the API:World Award for its video recording and playback capabilities, making it a strong choice among HIPAA-compliant telehealth platforms.
Ziggeo Key Features
Ziggeo's video capabilities bring powerful tools to healthcare applications:
You can add both player and recorder components using just a single HTML tag, which shows the platform's elegant design.
Ziggeo Pros
Ziggeo's compliance credentials meet healthcare's strict requirements:
Their support team helps healthcare organizations set up Business Associate Agreements (BAAs).
The platform works seamlessly with many systems including JavaScript frameworks, file services, form builders, content management systems, and mobile app support.
Ziggeo Best Use Case
Healthcare providers can use Ziggeo effectively in several ways:
QuickBlox
QuickBlox specializes in healthcare communication with HIPAA compliant telehealth features.
QuickBlox Key Features
QuickBlox provides these communication capabilities for telehealth applications:
QuickBlox Pros
QuickBlox serves over 30,000 software developers worldwide and creates 75 million chat streams daily.
The telehealth software makes remote monitoring, patient management, and team communication easier.
Healthcare organizations value knowing how to build custom telehealth software that fits their specific processes.
The platform gives users flexible deployment choices between cloud-based and on-premises solutions.
QuickBlox Best Use Case
QuickBlox excels at building complete virtual care systems that stay HIPAA compliant.
Q-Consultation's virtual consultations help manage patients in virtual waiting rooms effectively.
Healthcare providers choose QuickBlox to digitize their communications through chat and video calls. This helps them monitor patient status, track progress, and schedule remote appointments.
Livestorm
Livestorm stands among reliable HIPAA-compliant telehealth platforms and provides better solutions for healthcare organizations that need quick development options.
Livestorm Key Features
Livestorm delivers a browser-based video solution that eliminates the need for software downloads by patients and providers.
The platform supports HD quality video up to 1080p and includes these healthcare-focused features:
Livestorm Pros
Livestorm has strong security credentials with ISO 27001 certification and full GDPR compliance. These certifications make it suitable for handling sensitive health information.
The platform's user experience ratings are impressive with a 9.1/10 for ease of use and 9.0/10 for setup simplicity. Their technical support team maintains an 8.8/10 quality score and achieves over 95% customer satisfaction.
The platform's public API is a great way to get automation options with 10,000 monthly API calls included in the package.
Livestorm Best Use Case
Healthcare education and consultation shine on Livestorm's platform. Medical teams rely on it for remote patient interactions, healthcare professional training, and patient education webinars. Interactive medical presentations and consultations benefit from the platform's engagement tools.
Mux
Mux delivers exceptional video speed to the telehealth market and stands out as the best choice for HIPAA compliant telehealth platforms.
Mux Key Features
Mux processes videos at record speed and makes them ready to play in under 2 seconds, 100 times faster than other options.
The platform supports:
Mux automatically creates the right renditions for every device and bandwidth. The platform also provides speech recognition to generate automatic captions.
Mux Pros
Mux demonstrates its strength through a battle-tested system that manages everything from sudden traffic spikes to Internet outages. The platform follows strict privacy measures through Video Privacy Protection Act, California Consumer Privacy Act, and GDPR compliance.
Data protection uses pseudonymized IP addresses and tracks location only at country/state level. The platform controls content access through playback policies that need valid JSON Web Tokens.
Mux Best Use Case
Healthcare teams get several benefits from Mux. Medical providers can share critical patient information quickly because of Mux's exceptional processing speed. Providers can focus on patient care while Mux handles all video infrastructure challenges after implementation.
Conclusion:
No single telehealth API wins in every setting. Some tools prioritize end-to-end visit flow, including reminders, collaboration features, and searchable recordings. Others focus on secure calling infrastructure, flexible SDKs, or video capture that supports pre-visit screening.
Browser-based options can reduce patient friction, while video infrastructure providers lean into fast processing, streaming reliability, and fine-grained playback controls. Use the comparisons in this guide to map features to your care model.
Think about the full lifecycle, booking, visit delivery, documentation, and follow-up. When those pieces connect cleanly, virtual care becomes easier for patients and more consistent for clinicians.